[OT] When and where did the first bus route run?

One of the many YouTube channels I enjoy is one called The Tim Traveller, run by a Brit named Tim with a big interest in public transit. He regularly travels to various points in western and central Europe to make short videos relating to transit (and other topics).
This video is one where he reveals the location of the first public bus route, which turns out to have been an enterprise of a famous mathematican/philosopher. You won't believe how long ago that route operated!
https://www.youtube.com/watch?v=qsNEVRosKzM [7 minutes]
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Rhino