You could look at the MIT Lisp Machine, it used basically the same chips as a VAX 11/780 but was a pipelined load/store architecture internally.
from long ago and far away:
Date: 79/07/11 11:00:03 To: wheeler
i heard a funny story: seems the MIT LISP machine people proposed that IBM furnish them with an 801 to be the engine for their prototype. B.O. Evans considered their request, and turned them down.. offered them an 8100 instead! (I hope they told him properly what they thought of that)
... snip ...
... trivia: Evans had asked my wife to review/audit 8100 (had really slow, anemic processor) and shortly later it was canceled ("decomitted").
-- virtualization experience starting Jan1968, online at home since Mar1970