Identification and Quantitation of Furocoumarins in Popularly Consumed
Foods in the U.S. Using QuEChERS Extraction Coupled with UPLC-MS/MS
Analysis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8070520/Chemistry and health effects of furanocoumarins in grapefruit
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333421/Dietary Intake of Coumarins and Furocoumarins through Citrus Beverages:
A Detailed Estimation by a HPLC-MS/MS Method Combined with the Linear
Retention Index System
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303230/Novel coumarins as potential anticarcinogenic agents
https://pubmed.ncbi.nlm.nih.gov/1899055/Coumarins modulate the anti-glioma properties of temozolomide
Abstract
In the recent years, coumarin bioactive compounds have been identified
to posess anticancer properties.
https://pubmed.ncbi.nlm.nih.gov/32446712/Heracleum sphondylium
https://en.wikipedia.org/wiki/Heracleum_sphondyliumSosnowsky’s hogweed (Heracleum sosnowskyi) – a plant endangering human
health
ABSTRACT
Sosnowsky’s hogweed (Heracleum sosnowskyi) is con-
sidered to be an intrusive plant species in Poland which
endangers human health and life. The paper aims at show-
ing the complexity of influence of Sosnowsky’s hogweed
on the human organism and its consequences for human
health. The paper describes general physical and bio-
chemical characteristics of this species. The authors ana-
lyze the influence of the species on human health and
present general rules how to deal with possible negative
health consequences. The paper draws attention to the
necessity of undertaking educational activities related to
the health risk in direct and indirect contact with the
plant.
Keywords: Sosnowsky’s hogweed (Heracleum sos-
nowskyi), intrusive plant, toxic substances, environmental
hazard, health hazard
-=-=-
Sosnowsky’s hogweed (Heracleum sosnowskyi) – a plant endangering human
health
Environmental Medicine 2017, Vol. 20, No. 3, 55-59
www.medycynasrodowiskowa.pl DOI: 10.19243/2017307
ABSTRACT
Sosnowsky’s hogweed (Heracleum sosnowskyi) is con-
sidered to be an intrusive plant species in Poland which
endangers human health and life. The paper aims at show-
ing the complexity of influence of Sosnowsky’s hogweed
on the human organism and its consequences for human
health. The paper describes general physical and bio-
chemical characteristics of this species. The authors ana-
lyze the influence of the species on human health and
present general rules how to deal with possible negative
health consequences. The paper draws attention to the
necessity of undertaking educational activities related to
the health risk in direct and indirect contact with the
plant.
Keywords: Sosnowsky’s hogweed (Heracleum sos-
nowskyi), intrusive plant, toxic substances, environmental
hazard, health hazard
THE PRESENTLY KNOWN DISTRIBUTION OF FUROCOUMARINS
(PSORALENS)IN PLANTS*
M.A.PATHAK,Pn.D.**,FARRINGTON DANIELS,JR.,M.D.***AND
T.B.FITZPATRICK,M.D.**
https://www.jidonline.org/article/S0022-202X(15)49740-4/pdf
Furanocoumarins in anticancer therapy – For and against
Author links open overlay panelJoanna Sumorek-Wiadro, Adrian Zając,
Aleksandra Maciejczyk, Joanna Jakubowicz-Gil
https://www.sciencedirect.com/science/article/abs/pii/S0367326X20300745 Prospects of Hogweed (Heracleum sphondylium L.) as a New Horticultural
Crop for Food and Non-Food Uses: A Review
by Eleonora Matarrese
1 and Massimiliano Renna
2,* [ORCID]
1
Pikniq, Azienda Agricola & Home Food, Via Per Comnago 79, 28833
Brovello-Carpugnino, Italy
2
Department of Soil, Plant and Food Sciences, University of Bari Aldo
Moro, Via Amendola 165/A, 70126 Bari, Italy
*
https://www.mdpi.com/2311-7524/9/2/246Abstract
Heracleum sphondylium L., commonly known as hogweed, common hogweed, or
cow parsnip, is an herbaceous plant of the Apiaceae family native to
Europe and Asia. This wild edible plant is common in grasslands,
herb-rich meadows, hedges, wooded areas, roadsides, and railway
embankments and in both waste and cultivated grounds. This review
presents both the characteristics and ethnobotany, as well as the
findings, technical advances, and potential of hogweed research with the
goal of improving and disseminating knowledge regarding the value and
potential of this wild edible plant. Current knowledge suggests that H.
sphondylium L. shows good potential as a new cash crop, being an
interesting food ingredient and also a source of compounds with
biological activities. Therefore, hogweed may be proposed as a new
horticultural crop, although several aspects of cultivation must be
examined before full domestication.
horticulturae-2181532-supplementary.pdf
Hogweed recipes by Eleonora Matarrese
Hogweed and Burdock ‘Fake Artichokes’
Ingredients: hogweed and burdock stalks, hogweed leaves, dechlorinated
water, raw sea salt, wild
garlic bulbs, and wild oregano and thyme.
Preparation:
Place all the cleaned stalks of hogweed in a very clean jar, together
with a wild garlic bulb, some wild
oregano, and thyme to taste.
Prepare in another jar the brine, with dechlorinated water and 5% raw
sea salt. Let the salt dissolve,
and then pour this water on the hogweed in the other jar.
Let it stay for at least three days on a surface away from heat sources,
with the lid on and without
closing it, to release excess carbon dioxide.
After three days, it is ready, and you can close the lid and store it in
a cool and dark place. Use
burdock stalks just as you would use artichokes. You may also want to
let them dry for half a day to
release excess water and then place them in a jar, cover them with extra
virgin olive oil, and eat
them as if they were artichokes in oil. Hogweed stalks will be like
citrusy artichokes
https://www.mdpi.com/2311-7524/9/2/246#Wild Plant Species as Potential Horticultural Crops: An Opportunity for
Farmers and Consumers
https://www.mdpi.com/journal/horticulturae/special_issues/Wild_Plant_SpeciesRoberta Bulgari
roberta.bulgari@unito.itDr. Roberta Bulgari
E-Mail Website
Guest Editor
Department of Agricultural, Forest, and Food Sciences, DISAFA, Vegetable
Crops and Medicinal and Aromatic Plants, VEGMAP, University of Turin,
10095 Grugliasco, Italy
Interests: horticulture; abiotic stress; biostimulant; soilless
cultivation; microgreens; vegetable quality; ornamentals; postharvest
quality
Special Issues, Collections and Topics in MDPI journals
Ada Baldi
ada.baldi@unifi.itDr. Ada Baldi
E-Mail Website
Guest Editor
Dipartimento di Scienze e Tecnologie Agrarie, Alimentari Ambientali e
Forestali, Università degli Studi di Firenze, 50144 Firenze, Italy
Interests: vegetable crops; ornamentals; soilless cultivation;
microgreens; baby leaf; vegetable quality; wild food plants
Anna Lenzi
anna.lenzi@unifi.itDr. Anna Lenzi
E-Mail Website
Guest Editor
Department of Agriculture, Food, Environment and Forestry (DAGRI),
University of Florence, 50144 Florence, Italy
Interests: vegetable and ornamental crops; hydroponics; urban
agriculture; vegetables quality and safety
Antonios Chrysargyris
a.chrysargyris@cut.ac.cyDr. Antonios Chrysargyris
E-Mail Website
Guest Editor
Department of Agricultural Sciences, Biotechnology and Food Science,
Cyprus University of Technology, Limassol 3036, Cyprus
Interests: aromatic plants and vegetable cultivation; development of
strategies for plant nutrition and response to abiotic stress; soil-less
culture, substrates and hydroponics; postharvest storage and processing
of medicinal and aromatic plants; essential oil analysis and biocidal
activity; evaluation of natural products
Special Issues, Collections and Topics in MDPI journals
The last manuscript in your Special Issues
https://www.mdpi.com/journal/horticulturae/special_issues/Wild_Plant_SpeciesProspects of Hogweed (Heracleum sphondylium L.) as a New Horticultural
Crop for Food and Non-Food Uses: A Review
by Eleonora Matarrese and Massimiliano Renna
Horticulturae 2023, 9(2), 246;
https://doi.org/10.3390/horticulturae9020246 - 11 Feb 2023
Cited by 3 | Viewed by 3360
Abstract Heracleum sphondylium L., commonly known as hogweed, common
hogweed, or cow parsnip, is an herbaceous plant of the Apiaceae family
native to Europe and Asia. This wild edible plant is common in
grasslands, herb-rich meadows, hedges, wooded areas, roadsides, and
railway embankments and [...] Read more.
(This article belongs to the Special Issue Wild Plant Species as
Potential Horticultural Crops: An Opportunity for Farmers and Consumers)
Figure 6. Hogweed and burdock ‘fake artichokes’. Picture and recipe by
Eleonora Matarrese. The full recipe is available in the Supplementary
Materials.
https://www.mdpi.com/article/10.3390/horticulturae9020246/s1/.././././
OpenWHO
Furanocoumarins form a bond (crosslinking) with the DNA when exposed to
UV, which causes cancer cells death
https://openwho.org/courses/c4p-hpv-tool/learning_rooms/727f3a57-8e62-40c6-9d27-dc3d6f608693Discussions
https://openwho.org/courses/c4p-hpv-tool/question/4989eed7-ee23-4ecb-bfac-9194dd41df9aMeet one of the most dangerous plants in Russia
Lifestyle
Aug 24 2020
Eleonora Goldman
A person in a protective suit kills weed in Moscow Region.
Sergei Savostyanov/TASS
Follow Russia Beyond on Telegram
Sosnowsky's hogweed might look peaceful and harmless at first glance,
but don’t be deceived by its dill-like appearance. The only thing this
demon plant really wants is to make you cry from pain and maybe even
kill you.
Every summer Russians put on special protective suits, gather their
sharpest spades and rise up against Sosnowsky's hogweed (Latin name -
Heracleum). This weed, which looks like a huge dill plant, can be deadly
and grows literally everywhere from roadsides to private gardens. Why is
it so dangerous?
https://www.rbth.com/lifestyle/332613-russian-sosnowsky-hogweed-borschevikhttps://dachadecor.ru/lekarstvennie-rasteniya/borschevik-opisanie-i-primenenie-yadovitich-i-sedobnich-vidov-sornyakaThe 411 on Giant Hogweed, the Invasive Plant That Can Cause Severe Burns
and Blisters
The toxic plant has now spread to even more states across the U.S.
https://www.goodhousekeeping.com/home/gardening/a21598753/giant-hogweed/Why Giant Hogweed Is Dangerous
The danger of giant hogweed stems from its sap, which is present on all
parts of the plant. Toxic chemicals in it called furanocoumarins cause
severe burns when exposed to UV light from the sun. Even when the
painful blisters subside, permanent scarring can remain.
"The more sap you touch, the greater damage it causes," Naja Kraus, the
New York Department of Environmental Conservation's Giant Hogweed
Program Coordinator, tells GoodHousekeeping.com. "Once you get it on
you, it makes your skin unable to protect itself from the sun."
The reaction — called phytophotodermatitis — is similar to how some
antibiotics you take make your skin more sensitive to UV light. "It
basically fuses your DNA in that area," Kraus explains.
One 17-year-old boy recently went to the hospital with second- and
third-degree burns after he accidentally chopped down a giant hogweed
plant as part of his summer landscaping job. Alex Childress of
Spotsylvania County, Virginia, didn't notice anything unusual until he
went to take a shower that evening.
Evaluation of photocytotoxicity liposomal form of furanocoumarins
Sosnowsky's hogweed
https://pubmed.ncbi.nlm.nih.gov/35271822/Sosnowsky’s hogweed – toxicology and threat to health
Zdrojewicz Z1, Stebnicki M2, Stebnicki MR2.
Medical University of Wrocław, Poland: 1Faculty of Postgraduate Medical
Training, Department and Clinic of Endocrinology, Diabetology and
Isotope Therapy; 2Faculty of Medicine
https://medpress.com.pl/pubmed.php?article=243165Sosnowsky’s hogweed (Heracleum sosnowskyi Manden.) is a genus of plants
in the family Apiaceae which also includes Giant Hogweed (Heracleum
mantegazzianum Sommier & Levier). They are both found in Central Europe,
mainly in neglected green areas or riversides. Sosnowsky’s hogweed was
brought to Poland from the Soviet Union in the 1950s to be used in
animal feed production. Intended goals couldn’t be achieved and the
plant spread throughout grounds distant to the primarily cultivated
lands. Sosnowsky’s hogweed is especially hazardous in direct contact
with human skin. It results from the content of photoallergic substances
called furanocoumarins in its essential oil. Clinically it is presented
as burns, mainly of 2nd and 3rd degree. They mostly occur on the face,
upper and lower limbs. Typical symptoms include pain, redness, swelling
and heat in the area of exposure. Their extent depends on burn’s depth
and area and also on time of exposure to plant’s toxins. In this article
we present Sosnowsky’s hogweed’s activity and its influence on human
health.
/./././
/////////////////////////////////////
Barszcz Sosnowskiego - Amino - zupa
https://www.penera.pl/upload/images/2015/07/barszcz_sosnowskiego_od_amino_2015-07-06_16-23-28.jpg"Fałszywe karczochy" z barszczu i łopianu
Składniki: łodygi barszczu i łopianu, liście barszczu, odchlorowana
woda, surowa sól morska, cebulki dzikiego czosnku, dzikie oregano i
tymianek.
cebulki czosnku, dzikie oregano i tymianek.
Przygotowanie:
Umieścić wszystkie oczyszczone łodygi barszczu w bardzo czystym słoiku,
wraz z główką dzikiego czosnku, odrobiną dzikiego oregano i tymianku.
oregano i tymiankiem do smaku.
W innym słoiku przygotować solankę z odchlorowanej wody i 5% surowej
soli morskiej. Niech sól się rozpuści,
a następnie zalej tą wodą barszcz w drugim słoiku.
Pozostawić na co najmniej trzy dni na powierzchni z dala od źródeł
ciepła, pod przykryciem i bez zamykania.
aby uwolnić nadmiar dwutlenku węgla.
Po trzech dniach jest gotowy i można zamknąć pokrywkę i przechowywać go
w chłodnym i ciemnym miejscu. Używaj
łodyg łopianu tak samo, jak karczochów. Możesz również pozwolić im
wyschnąć przez pół dnia, aby
uwolnić nadmiar wody, a następnie umieścić je w słoiku, przykryć oliwą z
oliwek z pierwszego tłoczenia i zjeść
je tak, jakby były karczochami w oliwie. Łodygi barszczu będą jak
cytrusowe karczochy
Anti-cancer furanocoumarines w barszczu wysokim - do przeczytania