Sujet : Re: Bez stanika, bez majtek, bez raka piersi prostaty jelita grubego bez hemoroidów
De : manta103g (at) *nospam* gmail.com (darius)
Groupes : soc.culture.polishDate : 05. Aug 2024, 22:32:32
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niech gópol nie smrodzi w moim wątku
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https://pbs.twimg.com/media/GTdz2EaagAADgIl?format=jpgPhotodynamic therapy for cancer: role of natural products
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579671/Behzad Mansoori,1,2,4 Ali Mohammadi,1,4 Mohammad Amin Doustvandi,1
Fatemeh Mohammadnejad,1 Farzin Kamari,3 Morten F. Gjerstorff,4 Behzad
Baradaran,1,* and Michael R. Hamblin5,6,7,*
Author information Copyright and License information PMC Disclaimer
The publisher's final edited version of this article is available at
Photodiagnosis Photodyn Ther
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Abstract
Photodynamic therapy (PDT) is a relatively new and promising modality
for the treatment of cancer. PDT involves administering a
photosensitizing dye, i.e. photosensitizer, that selectively accumulates
in tumors, and shining a light source on the lesion with a wavelength
matching the absorption spectrum of the photosensitizer, that exerts a
cytotoxic effect after excitation. The reactive oxygen species produced
during PDT are responsible for the oxidation of biomolecules, which in
turn cause cell death and the necrosis of malignant tissue. PDT is a
multi-factorial process that generally involves apoptotic death of the
tumor cells, degeneration of the tumor vasculature, stimulation of
anti-tumor immune response, and induction of inflammatory reactions in
the illuminated lesion. Numerous compounds with photosensitizing
activity have been introduced commercially. Although many papers have
been published with regard to PDT in the last decade, there has been
relatively little focus on natural medicinal plant extracts and
compounds derived therefrom. Herbal plants and their extracts are
natural substances, and in comparison with synthetic chemicals are
considered “green”. This review focuses on the different mechanisms of
PDT and discusses the role of various plant extracts and natural
compounds either alone or in combination for carrying out PDT on
different types of cancers.