Re: West Virginia creationism

On 2024-04-18 19:00:03 +0000, Vincent Maycock said:

On Thu, 18 Apr 2024 03:03:03 -0400, Ron Dean
<rondean-noreply@gmail.com> wrote:
 

Martin Harran wrote:

On Sun, 14 Apr 2024 00:25:20 -0400, Ron Dean

<snip>

 

With the DNA coded information due to mutations (which are real) become
increasingly less perfect when passed down to their offspring the
defective genes are always down to the offspring never reversed; with
the passage of time, the genome may  just become so overburden with
defective genetics - bad mutations that failure to reproduce becomes
inevitable. Maybe there is a loss of sexual drive, or instinct, all of
which is expressed by genetics. As a species age, perhaps like human
males species reach an age when sex desire dies and offsprings cannot
happen.

 Where does your intelligent designer fit into that process?
 

So, you agree - I fell out of my chair I was so shocked!

 No one's agreeing with you, Ron.  They're just asking you a question
about your beliefs.
 

If you go back
in tine to one's grandparents their genome had fewer deleterious
mutations than ours: going backwards generation after generation after
generation, the genome of each preceding generation had ever fewer
harmful mutations,

 Cite?
 

By going back say to the earliest members of their
kind (family)

 Your use of the word "kind" ties you historically to the young earth
creationists (Seventh-day Adventist Frank Lewis Marsh came up with it,
if memory serves).  Is that something you're comfortable with?
 

their genome must have been far closer to perfect than any
decedent generations. From then, each succeeding generation the
deleterious mutations multiplied.

 Unless they're eliminated by natural selection.
 

I think possibly the proofreading and
repair, which was an elegantly and highly sophisticated design set up
for the best results, but over the vast spans of time even the P&R
mechanisms, which initially were perfect,

 This is a religious belief, not a science-based claim.
 

but with the passage of time
even the P&R became less perfect due to bad mutations that slipped
passed the P&R mechanisms, consequent the P&R systems were affected. The
results we see today.

It's almost despairing to try to cope with such depths of ignorance. However, the other day he was asking for some references to sources that he coud read.
For proofreading, Alan Fersht's book "Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding" might be a place to start. 90% of the book will be too advanced for Ron Dean, but he might able to understand the bits about repair mechanisms.
More generally, Dan Graur's book "Molecular and Genome Evolution" would be an excellent answer to many of his questions, if he could make an effort to understand it.
--
athel cb : Biochemical Evolution, Garland Science, 2016