Sujet : Evolution of California dairy virus
De : rokimoto557 (at) *nospam* gmail.com (RonO)
Groupes : talk.originsDate : 13. Oct 2024, 14:02:00
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Sixth attempt to post:
https://www.cidrap.umn.edu/avian-influenza-bird-flu/avian-flu-confirmations-california-dairy-workers-reach-66 cases of infected dairy workers and one more submitted for confirmation that would make the total 7. 100 infected herds have been detected so far (the number quoted is more than 1100 total herds in California) so it is evident that other states have severely under reported infected herds, and never tested as many herds as California, nor dairy workers.
The CDC is still claiming that that the infection rate is low, but most of the herds have been detected because they share workers with known infected farms, and the CDC was able to isolate live virus from 3 of the first 4 California cases. The infected are obviously shedding virus and infected dairy workers have likely been responsible for spreading the virus to other farms and poultry flocks. The virus is only infective off skin and clothing for less than 30 minutes. Infected workers would explain how states that did not get infected cattle were infected by the dairy virus.
https://www.cdc.gov/bird-flu/spotlights/h5n1-response-10112024.htmlThe CDC has confirmed that the two mutations in the H5 gene found in the Missouri patient do reduce the ability of H5 antibodies to bind, and they are going to create antibodies to a synthetic H5 with the two mutations in order to test the the other Missouri cases that had symptoms.
The California dairy worker isolates also differ by 2 or 3 amino acid substitutions that may affect the efficacy of existing vaccine strains of H5, but they do not have the mutations that would make them more effective in infecting humans, and they also do not have the anti-viral drug resistance mutations. It is likely that as is the case for the Missouri patient the H5 vaccine that the Federal government is stockpiling at this time is going to be nearly worthless against the virus if it does mutate to be more of an issue for humans.
They are going ahead with vaccinating dairy workers with seasonal flu vaccine in order to decrease the possibility of double infections that could produce recombinant virus that are more virulent in humans. They are only doing it in states with known infected herds even though they know that a lot more states have infected herds than have admitted to having them. Florida is a highly populated example. The FDA detected H5N1 positive dairy products produced in Florida in May. The CDC already knew that some counties in Florida had high levels of influenza virus in their waste water and Poultry flocks have gone down with the dairy virus, and the poultry flocks in other states have been infected by the dairy herds. Some dairy worker on infected farms also worked on poultry farms in both Texas and Michigan where they asked that question.
Ron Okimoto