Re: Ool - out at first base?

On 12/18/24 8:49 PM, MarkE wrote:

On 19/12/2024 3:16 am, Mark Isaak wrote:

On 12/17/24 5:12 PM, MarkE wrote:

On 17/12/2024 6:33 am, Mark Isaak wrote:

What makes you think that you know enough about the universe to think that the problems you put forward will not likewise be obviated by further research?

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I don't, not with certainty. Hence I put forward possible OoL showstoppers for scrutiny.
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To that end, do you think the following recent examples have any merit at all? I'm not asking if you agree that they're a problem, rather, is there any legitimacy in addressing them as potentional problems for OoL?
- the tar paradox

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Probably not a problem. It's easy to imagine mechanisms that could separate productive products from counterproductive ones.
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- supply of concentrated nucleotides unbroken for millions of years

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A problem, yes, but only in the sense that solving any puzzle is a problem.  A showstarter (where research is the show), not a showstopper. Also, millions of years may be unnecessary. I suspect that one bottleneck of abiogenesis is for the proper conditions to come together, but once they do, a huge step could be taken in months, perhaps hours. I might be completely wrong about that, but then, others might be wrong about thinking optimum conditions must persist for millions of years.
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 It is difficult to quantify this time.

That's the point.

An estimate of the minimal length of RNA required for self-replication is 100 units:
[...]

Which may not be relevant. The first replication might very well not be RNA.
--
Mark Isaak
"Wisdom begins when you discover the difference between 'That
doesn't make sense' and 'I don't understand.'" - Mary Doria Russell