Re: H5N1 human infections in Cambodia

On 6/28/2025 6:56 PM, RonO wrote:

On 6/17/2025 10:29 AM, RonO wrote:

https://www.cidrap.umn.edu/avian-influenza-bird-flu/h5n1-avian-flu- infects-fifth-patient-cambodia
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A reassorted H5N1 that is a combination of clade 2.3.4.4b (dairy virus clade) and clade 2.3,2,1c (an older H5N1 clade) is infecting Cambodia. 4 people have been infected and all have died.  The 5th person was confirmed to be infected with H5N1, but the clade has not been determined and she has been in the hospital since mid May.  She did not have contact with poultry, so they do not know how she got infected. This seems to be a highly pathogenic virus strain.  We are lucky that a different reassorted virus infected the dairy herds in the US.
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Ron Okimoto
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https://www.cidrap.umn.edu/avian-influenza-bird-flu/cambodia- announces-7th-h5n1-avian-flu-case-year
 The 5th case ended in fatality, and there has been a 6th and 7th case of H5N1 infection in Cambodia.  So far there has been a 100% mortality after infection.  The 7th case is in critical condition, but they do not say what the condition of the 6th case is.
 This seems to be a virulent strain that infects people that process and eat infected poultry.  3 children have been among the fatalities.
 Ron Okimoto
 

https://www.cidrap.umn.edu/avian-influenza-bird-flu/cambodia-confirms-2-more-h5n1-avian-flu-infections
Two more cases in Cambodia.  They were neighbors of one of the other infected patients, and seem to have been caught early enough and are listed in stable condition in the hospital after being put on antivirals.  They apparently ate infected chickens.
These are listed as the 9th and 10th casses, so there must have been three new cases since the 7th was announced, and they report 6 fatalities (one more since the last report).
In the previous H5N1 lethal infections in Southeast Asia the people who got infected by eating infected poultry showed gut infection symptoms like the lethal infections of the cats with the dairy virus.  They do not say what symptoms the 10 patients had.
Ron Okimoto