Re: OT: New imaging method enables detailed RNA analysis of the whole brain

On 24/11/2024 5:33 pm, Jan Panteltje wrote:

New imaging method enables detailed RNA analysis of the whole brain
  https://www.sciencedaily.com/releases/2024/11/241121141005.htm
Source:
  Karolinska Institutet
Summary:
  Researchers have developed a groundbreaking microscopy method that
enables detailed three-dimensional (3D) RNA analysis at cellular resolution
in whole intact mouse brains.
The new method, called TRISCO, has the potential to transform our understanding of brain function,
both in normal conditions and in disease, according to the new study.
 Paper:
  https://www.science.org/doi/10.1126/science.adn9947

There are a lot of different RNA molecules in the brain, and this method can identify three of them, though they hope to be able to push this up to a hundred or so in the future.
https://www.futurelearn.com/info/courses/translational-research/0/steps/14201
There are 23,000 different messenger RNA's encoded in the human genome, and whole lot different sorts of RNA that does other jobs.
The researcher's seem to have a way to go yet.
--
Bill Sloman, Sydney